Endocannabinoid

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CBD for Obsessive Compulsive Disorder

Could the Endocannabinoid System Offer a New Treatment Target for Obsessive Compulsive Disorder?

The disabling condition of obsessive-compulsive disorder (OCD) affects about 2–3% of people worldwide. Evidence suggests that abnormalities in cortico-striatal-thalamic-cortical circuitry and specific gene variants contribute to the pathogenesis of the disorder. This latest study, published in Cannabis and Cannabinoid Research, suggests that the endocannabinoid system (ECS) plays a role in OCD symptoms

Neurotransmitters and neurochemicals

Interaction of Neurotransmitters and Neurochemicals with Lymphocytes, including the Endocannabinoid System

Neurotransmitters and neurochemicals can act on lymphocytes by binding to receptors expressed by lymphocytes. This review describes lymphocyte expression of receptors for a selection of neurotransmitters and neurochemicals, the anatomical locations where lymphocytes can interact with neurotransmitters, and the effects of the neurotransmitters on lymphocyte function. Implications for health and