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endocannabinoids

Interview with Jeffrey Chen, MD and Raphael Mechoulan, PhD on Endocannabinoids

This video, Jeffrey Chen, MD, the Director of the UCLA Cannabis Research Initiative, is the best explanation of the mechanisms and action potential of endocannabinoids in the human body. This is followed by and interview with Raphael Mechoulan, PhD, professor of Medicinal Chemistry at the Hebrew University of Jerusalem. Mechoulan

Cannabidiol Offers Inflammatory Properties for Contact Dermatitis

This study is the first demonstration of the anti-inflammatory properties of Cannabidiol in an experimental model for allergic contact dermatitis (ACD). Published in the J. Pharmacology and Experimental Therapeutics, March 2018. Abstract / Phytocannabinoids modulate inflammatory responses by regulating the production of cytokines in several experimental models of inflammation. Cannabinoid type-2

Endocannabinoid System

Cannabinoid Receptors and the Endocannabinoid System: What Is it and What Does it Do?

The endocannabinoid system consists of endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the synthetic and degrading enzymes responsible for synthesis and degradation of endocannabinoids. Endocannabinoids are so named because they were first identified as activating the same receptors as cannabinoids, the primary psychoactive components of cannabis. Published in Journal of Neuroendocrinology 20

Legal Cannabis

Two JAMA Studies with Podcast: Legal Cannabis Reduces Opioid Prescribing

Recently the Journal of the American Medical Association (JAMA) published two studies and commentary on the relationship between legal cannabis use and opioid prescribing rates and patterns. We provide an 11-minute podcast from the authors and the study abstract summaries below. One study examines state implementation of medical and adult-use