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Understanding NRF2: Clinical Relevance in Oxidative Stress, Inflammation, and Chronic Disease
NRF2 is a master regulator of antioxidant and anti-inflammatory defenses, making it a vital target in managing chronic diseases like cancer, neurodegeneration, diabetes, and heart disease. This medical review explores NRF2’s clinical significance, disease relevance, and therapeutic modulation using pharmaceuticals and natural compounds.
From Probiotics to Fecal Transplant – A Paradigm Shift (Part 1)
Early Days of Probiotics: Promise and Marketing Hype Modern microbiome science emerged in the 2000s with the realization that trillions of gut microbes form a
Adjunctive Therapies Improve Clinical Outcomes in SIBO
A randomized controlled trial published in the journal Nutrients studied the effects of herbal supplements and probiotics alongside antibiotics and a low FODMAPs diet for SIBO. 179 patients diagnosed with SIBO via breath testing were enrolled in the study. Patients received breath testing at the beginning and the end of the 3-month study. Patients were divided into hydrogen (H2) and methane (CH4) predominant groups, since treatment varies slightly depending on the breath gas type.
Are Cannabinoids the Key to a Comfortable, Healthy GI Tract?
The statements mentioned in this content have not been evaluated by the FDA, and are not intended to prevent, diagnose, or treat any disease. Always
Microbiota & Seasonal Allergies
First introduced in 1989, the “hygiene hypothesis” proposed that exposure to specific microbes, perhaps during crucial windows of development, educates the immune system in a
Phytocannabinoids and Keeping Your Immune System Healthy
Scientists have called the endocannabinoid system one of the “gatekeepers” of the immune system.1 The endocannabinoid system is activated in response to immune challenges like viral
