Key Points:
- A 50-y-old Caucasian male came into an arthritic care clinic to request a screening for osteoporosis. The patient was in excellent physical health, with no recent illnesses, no medical history of inflammatory conditions or musculoskeletal issues or bone fractures, and at the time was not taking any medications.
- At the time he was exercising regularly, did not smoke, and had consumed a Mediterranean-style diet of anti-inflammatory foods for most of his life with occasional alcohol consumption.
- His mother had been diagnosed with moderate osteoporosis for the past ten years… patient’s father likewise had been diagnosed with severe osteoporosis for the past three years.
- DEXA scans of the patient’s left and right femoral neck and lumbar spine resulted in T-scores of -2.1, -1.8, and -3.8, respectively.
- Being a naturopathic doctor, the patient opted instead to begin a trial of a natural dietary supplement. He was placed on a regimen of 450 mg of Cyplexinol twice daily. Cyplexinoj (brand name Ostinol®, ZyCal Bioceuticals Healthcare Co., Inc., Toms River, NJ) is the first orally consumable demineralized bone matrix (DBM) consisting of a naturally-derived bone morphogenetic protein complex (BMP-Complex).
- After four months repeat DEXA scans were performed on the same bone densitometer from Hologic.
- After four months of consistently following the Cyplexinol regimen, the T-scores of the left femoral neck, right femoral neck, and lumbar vertebrae were evaluated at -2.1, -1.9, and -3.3, respectively.
- The lumbar spine T-score increase of 0.5, from -3.8 to -3.3, was a significant improvement over baseline. This correlates with an increase in BMD of 0.062 g/cm2 (from 0.669 g/cm2 to 0.731 g/cm2) or 9.3%.
