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Questioning LDL Targets

“Clinical guidelines have progressively lowered the recommended LDL-C target for high-risk CVD patients to below 70 mg/dL, but scientific support for this target is arguably questionable.” A review published recently in the Journal of Clinical Medicine adds to research questioning the relationship between LDL-cholesterol (LDL-C) and cardiovascular disease (CVD). Previous blogs and Research Forums have highlighted numerousRead

Pulmonary Health & Nutrition Support

The results of a network meta-analysis, which evaluated the use of various nutritional supplements for chronic obstructive pulmonary disease (COPD), were published in BMC Pulmonary Medicine. This analysis included 37 randomized and controlled trials, a total of nearly 2,000 participants with COPD, and 21 nutritional interventions. Network analysis allows for a rough comparisonRead

Coenzyme Q10 (Ubiquinol) and Hypertension: Effects on Blood Pressure and Cardiovascular Health

CoQ10 is synthesized endogenously and can be obtained through diet and supplements. With certain conditions, such as hypertension (HTN), the body cannot synthesize enough CoQ10, prompting the need for supplementation. As CoQ10 levels decline and oxidative stress increases with age, CoQ10 supplementation has shown therapeutic benefits in aging-related disorders.

LDL-C/ApoB and Plaque

A study published in JACC: Advances seeks to move research forward toward identifying whether severe elevations in LDL-C are associated with increased atherosclerosis in lean, otherwise healthy people following KDs. This one-year prospective study followed 100 subjects classified as…

Micro and Nanoplastics from Heated Disposable Takeout Containers Are Implicated in Cardiovascular Disease Risk

Plastic is ubiquitous in today’s environment, and we see negative repercussions on cardiovascular health. A recent New England Journal of Medicine article showed that patients with microplastics and nanoplastics (MNPs) detected in carotid plaques had higher risk of myocardial infarction, stroke, or death from any cause.

Understanding Apolipoprotein B

Apolipoprotein B (ApoB) is a crucial structural protein found in atherogenic lipoproteins, including low-density lipoprotein (LDL), very low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and lipoprotein(a) [Lp(a)]. Unlike other lipid markers such as LDL-C, which measure cholesterol content, ApoB provides a direct count of the number of atherogenic lipoprotein particles, makingRead

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