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Neutralization of Inflammation by Inhibiting In vitro and In vivo Secretory Phospholipase A2 by Ethanol Extract of Boerhaavia diffusa L.
Background: Inflammation is a normal and necessary prerequisite to healing of the injured tissues. Inflammation contributes to all disease process including immunity, vascular pathology, trauma, sepsis, chemical, and metabolic injuries. The secretory phospholipase A2 (sPLA2) is a key enzyme in the production of pro-inflammatory mediators in chronic inflammatory disorders suchRead
Inhibition of Group IIA Secretory Phospholipase A2 and its Inflammatory Reactions in Mice by Ethanolic Extract of Andrographis paniculata, a Well-known Medicinal Food
ABSTRACT/ Andrographis paniculata Nees is an important medicinal plant found in the tropical regions of the world, which has been traditionally used in Indian and Chinese medicinal systems. It is also used as medicinal food. A. paniculata is found to exhibit anti-inflammatory activities; however, its inhibitory potential on inflammatory GroupRead
Bladder Organoids & Bladder-on-a-Chip Reveal Urinary Tract Infection Pathogensis
Scientists have developed two complementary bladder models to study urinary tract infection (UTIs) caused by E. coli: bladder organoids and a bladder-on-a- chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune system and resist antibiotics. The studies, published in the journals Cell ReportsRead
Meat Alternatives and Meat Are Not Nutritionally Equal, Each Lacks Important Metabolites
Market trend analysis shows the global plant-based meat alternative market size is expected to grow at a compound annual growth rate (CAGR) of 19.4% from 2020 to 2027. The rise is attributed to growing consumer demand for plant-based diets and rising awareness about animal rights and climate change. However, howRead
FDA’s Accelerated Drugs Remain in the Market Without Oversight for Effectiveness, says BMJ Report
Since the US Food and Drug Administration (FDA) established its accelerated drugs approval pathway in 1992, nearly half (112) of the 253 drugs authorized have not been confirmed as clinically effective, an investigation by The BMJ has found. In a press statement, The BMJ says the “process is plagued byRead
Tai Chi Mirrors the Benefits of Conventional Exercise in Adults with Central Obesity
The gentle meditative exercise of tai chi may be as beneficial as other more vigorous forms of activity when measuring central obesity. This study found that tai chi reduced waist circumference in middle-aged and older adults with abdominal obesity in a study done by investigators at the University of HongRead
Plasma Protein Profiles Show Potential for Cardio-respiratory Fitness Levels from Exercise
Exercise more is often the advice from health experts. But what kind of exercise? Does the same exercise work for everyone? Exercise unto itself is beneficial, however, we don’t really understand the reasons why the same exercise can have different effects in different people. A study published in Nature MetabolismRead
Herring Roe Oil Improves Severity of Mild Psoriasis + Interview with Study Author
The following is a summary of a human-subject study on herring roe oil with clinical meaningful results for supporting patients with mild psoriasis vulgaris. Following the summary is an interview with study co-author, Hogne Hallaraker, founder and Chief Science Officer of Arctic Bioscience. In recent small but significant human-subject study,Read
Commentary/Into the Future: Amazon and the Rise of Personal Healthcare
In this commentary on the future of healthcare, Dr. Robin Gaster shows the powerful influence Amazon and technology play in the role of medicine and the rise of personal healthcare. By Robin Gaster/ For 100 years, retailers have segmented the broad marketplace into groups – soccer moms, or Millennials, orRead
Altered Information Processing in Infants Linked to Prenatal Phthalate Exposure
Exposure to phthalates, the class of chemicals widely used in packaging and consumer products, is known to interfere with normal hormone function and development in human and animal studies. Now researchers have found evidence linked to prenatal phthalate exposure and altered cognitive outcomes in their infants. Most of the findingsRead