Early Lab Study: Hemp Shows Therapeutic Potential for Reducing Ovarian Cancer Risk

CBD, hemp and ovarian cancer

Could non-psychoactive hemp be a viable use to reduce ovarian cancer risk? As we learn more about the bioactives in hemp, the possibility becomes ever real. At the 2018 annual Experimental Biology meeting in San Diego, graduate students, Sara Biela and Chase Turner, presented the first study to examine hemp andRead …

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Beyond CBD: Exploring the Endocannabinoid System in Health and Disease, with Carl Germano PhD

Eureka! We’ve been on the search and finally found a refreshingly honest interview on the subject of the endocannabinoid system and the use of cannabidiol in clinical practice. Not surprisingly, it came from Carl Germano, PhD, RD, CNS, CDN. Germano has been in private practice in integrative and nutritional therapies

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Interview with Jeffrey Chen, MD and Raphael Mechoulan, PhD on Endocannabinoids

endocannabinoids

This video, Jeffrey Chen, MD, the Director of the UCLA Cannabis Research Initiative, is the best explanation of the mechanisms and action potential of endocannabinoids in the human body. This is followed by and interview with Raphael Mechoulan, PhD, professor of Medicinal Chemistry at the Hebrew University of Jerusalem. MechoulanRead …

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CBD Myth-Busting Study: High Doses of Cannabidiol Do Not Cause THC-Like Effects in Humans

CBD

Have you been hesitant to prescribe cannabidiol (CBD) because of concerns about gastric acids converting the CBD into psychoactive tetrahydrocannabinol (THC)? In 2016, a study by Merrick et al. suggested that when CBD is exposed to an acidic environment, it degrades to Δ9-tetrahydrocannabinol  and other psychoactive cannabinoids. The following isRead …

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Cannabidiol Offers Inflammatory Properties for Contact Dermatitis

This study is the first demonstration of the anti-inflammatory properties of Cannabidiol in an experimental model for allergic contact dermatitis (ACD). Published in the J. Pharmacology and Experimental Therapeutics, March 2018. Abstract / Phytocannabinoids modulate inflammatory responses by regulating the production of cytokines in several experimental models of inflammation. Cannabinoid type-2Read …

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Cannabinoid Receptors and the Endocannabinoid System: What Is it and What Does it Do?

Endocannabinoid System

The endocannabinoid system consists of endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the synthetic and degrading enzymes responsible for synthesis and degradation of endocannabinoids. Endocannabinoids are so named because they were first identified as activating the same receptors as cannabinoids, the primary psychoactive components of cannabis. Published in Journal of Neuroendocrinology 20Read …

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CBD for Drug and Alcohol Recovery? Preclinical Study Shows Cannabidiol (CBD) May Be An Effective Solution

CBD for drug and alcohol recovery

Have you thought of prescribing CBD for drug and alcohol recovery? There is new evidence that the non-psychoactive and non-addictive ingredient, cannabidiol (CBD), could help prevent relapses for recovering drug addicts and alcoholics. This preclinical study’s findings provide further evidence about the possible medical benefits of non-psychoactive cannabinoids, and howRead …

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Two JAMA Studies with Podcast: Legal Cannabis Reduces Opioid Prescribing

Legal Cannabis

Recently the Journal of the American Medical Association (JAMA) published two studies and commentary on the relationship between legal cannabis use and opioid prescribing rates and patterns. We provide an 11-minute podcast from the authors and the study abstract summaries below. One study examines state implementation of medical and adult-useRead …

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Could Cannabidiol Be the Answer to Treatment-resistant Epilepsy & Lennox-Gastaut Syndrome?

The level of frustration and hopelessness is high among one-third of epilepsy cases that are resistant to medication. A just-released study in Lancet, outlines how a pharmaceutical formulation of cannabidiol (20 mg/kg daily), alongside other anti-epilepsy treatments, reduced the number of drop seizures – seizures which involve sudden falls due

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Effectiveness of Medical Cannabis for Parkinson’s Disease

Medical Cannabis for Parkinson's
Current treatments of Parkinson disease (PD) and parkinsonism still provide suboptimal effects, especially regarding the patients’ quality of life. This has led to the search for alternative and often unconventional therapies, such as medical cannabis for Parkinson’s Disease (PD). The use of medical cannabis (MC) is controversial. Support for its

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