Fasting Improves Health by Affecting the Circadian Clocks in the Liver and Muscle

In a University of California, Irvine-led study, researchers found evidence that fasting improves health by affecting circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports.Read …

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Age-Related Immunity Loss May be the “Graying” of T Cells, says Harvard Research

Age-related immunity loss is more than evident in the elderly who suffer more serious complications from infections and benefit less from vaccination than the general population. Scientists have long known that a weakened immune system is to blame but the exact mechanisms behind this lagging immunity have remained largely unknown.Read …

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Jeffrey Bland, PhD on Age as a Modifiable Risk Factor for Chronic Disease

Jeff Bland
In this post, we bring you a column from Jeffrey Bland, PhD on aging, published in Integrative Medicine, A Clinician’s Journal. He explores the question of why age is an independent risk factor for all chronic diseases, including heart disease, dementia, arthritis, diabetes, and cancer. Despite the fact that there

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Ayurveda’s Concept of Healthspan: Adding Life To Years and Years to Life

healthspan

Imagine that instead of the word aging, we used successful healthspan when helping patients stay healthy as they get older? It’s a word that conveys long-term health not dread and illness. As the authors of this study note: “Unlike the modern medicine approach of seeking pills and supplements or replacingRead …

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Therapeutic Advancements and Analytical Tools to Defy Age-Related Diseases, by Jeffrey Bland, PhD

Age-Related Diseases, by Jeffrey Bland

In this column from Integrative Medicine, a Clinician’s Journal, by Jeffrey Bland, PhD, he discusses the latest therapeutic and analytical tools for age-related diseases. As an example, Bland examines damage to our DNA and screening for the presence of clonal hematopoiesis of indeterminate potential. He says, “this type of technologyRead …

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Secret to Longevity? Answer Could be Fisetin Flavonoid in Fruits & Vegetables

fisetin

Previous research published earlier this year in Nature Medicine involving University of Minnesota Medical School faculty Paul D. Robbins and Laura J. Niedernhofer and Mayo Clinic investigators James L. Kirkland and Tamara Tchkonia, showed it was possible to reduce the burden of damaged cells, termed senescent cells, and extend lifespanRead …

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Pine Bark Extract Improves Mild Cognitive Impairment

The benefits of pine bark extract continue to evolve with emerging science. This most recent study examined the benefits of Pycnogenol® (Horphag) supplementation over a two-month-period in otherwise healthy individuals with minimal cognitive impairment and initial cognitive dysfunction selected on the basis of their Mini-Mental State Examination (MMSE) score. ImpairmentsRead …

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Jeffrey Bland, PhD and Volter Longo, PhD on Longevity

Jeff Bland

In Jeffrey Bland’s April column in Integrative Medicine, A Clinician’s Journal, he references the work of Volter Longo, PhD, the author of the Longevity Diet: Discover the New Science Behind Stem Cell Activation and Regeneration to Slow Aging, Fight Disease and Optimize Weight. Longo is the director of the LongevityRead …

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Dark Chocolate Improves Walking in Patients With Peripheral Artery Disease

This interventional study measured the acute effect of dark chocolate on walking distance autonomy (WDA), artery dilatation and NOX2‐mediated oxidative stress in a population affected by moderate‐severe. Previous studies with antioxidant infusion provided evidence that oxidative stress is implicated in impairing WDA, while its inhibition was associated with maximal walking distance (MWD) improvement. In PAD patients dark but not milk chocolate acutely improved walking autonomy with a mechanism possibly related to an oxidative stress‐mediated mechanism involving NOX2 regulation.

Mechanism for Calorie Restriction Discovered

A new study led by Harvard School of Public Health (HSPH) researchers identifies a key molecular mechanism behind the health benefits of dietary restriction, or reduced food intake without malnutrition. Also known as calorie restriction, dietary restriction is best known for its ability to slow aging in laboratory animals. TheRead …

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