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Neutralization of Inflammation by Inhibiting In vitro and In vivo Secretory Phospholipase A2 by Ethanol Extract of Boerhaavia diffusa L.

Background: Inflammation is a normal and necessary prerequisite to healing of the injured tissues. Inflammation contributes to all disease process including immunity, vascular pathology, trauma, sepsis, chemical, and metabolic injuries. The secretory phospholipase A2 (sPLA2) is a key enzyme in the production of pro-inflammatory mediators in chronic inflammatory disorders suchRead

Inhibition of Group IIA Secretory Phospholipase A2 and its Inflammatory Reactions in Mice by Ethanolic Extract of Andrographis paniculata, a Well-known Medicinal Food

ABSTRACT/ Andrographis paniculata Nees is an important medicinal plant found in the tropical regions of the world, which has been traditionally used in Indian and Chinese medicinal systems. It is also used as medicinal food. A. paniculata is found to exhibit anti-inflammatory activities; however, its inhibitory potential on inflammatory GroupRead

Bladder Organoids & Bladder-on-a-Chip Reveal Urinary Tract Infection Pathogensis

urinary tract infections

Scientists have developed two complementary bladder models to study urinary tract infection (UTIs) caused by E. coli: bladder organoids and a bladder-on-a- chip. The two studies reveal how bacteria invade the bladder, and how they evade the immune system and resist antibiotics. The studies, published in the journals Cell ReportsRead

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