Longevity
The Most Overlooked Underlying Cause of Joint Dysfunction: Senescent Cells
Senescent cells, colloquially known as “zombie cells,” have emerged as pivotal players in the aging process and age-related ailments, particularly joint disorders like arthritis. These cells, once active but now in a state of growth arrest, accumulate in arthritic joints, triggering a cascade of inflammatory responses and tissue degradation. TheRead
Demystifying Senescent Cells: Taking An Abstract Concept and Making It Real In Practice
Senescent cells, often referred to as zombie cells, are a fascinating aspect of cellular biology that plays a crucial role in the aging process and age-related diseases. Cellular senescence occurs when a cell undergoes irreversible growth arrest, ceasing to divide and carry out normal cellular functions. While this state initiallyRead
GlyNAC Research Review and Clinical Considerations
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial. The Journals of Gerontology. 2023 Jan 26;78(1):75-89. Clinical Implications From a clinical perspective, GlyNAC could be utilized in a practice setting as a potential Read
The Vagus Nerve: New Understandings, Emerging Research and Implications for Overall Wellness.
In recent years, the vagus nerve has become a topic of great interest, especially as it relates to stress, anxiety, depression, mood and sleep. Social media and popular blogs propose a slew of hacks and home remedies aimed at toning the vagus nerve. And with such product offerings as essentialRead
L-Ergothioneine: The Mitochondrial Marvel
L-ergothioneine is a naturally occurring amino acid derivative that accumulates within cells, particularly in mitochondria. Mitochondria are cellular organelles known as the powerhouses of the cell, responsible for generating energy in the form of adenosine triphosphate (ATP) through oxidative phosphorylation. The accumulation of L-ergothioneine within the mitochondria is dueRead
Unraveling the Role of Butyrate in Cellular Health and Aging
Cultivating Longevity Through Optimized Digestion Recent advances in microbiology have led to the recognition of the gut microbiota as an essential component contributing to the aging process. The gut microbiota is a diverse ecosystem of microorganisms residing in the gastrointestinal tract that profoundly influences host health. This article aims toRead
The Glymphatic System, Shoden Ashwagandha and the Dynamic Interplay of Sleep and Aging
In order to fully understand the role of sleep as it relates to aging, its necessary to embark on an in-depth exploration of the intricate interplay between sleep, aging, and the potential therapeutic utility of a novel form of Ashwagandha with the highest concentration of active constituent that has shownRead
Longevity Medicine 101: Part 1
Introduction Longevity, the desire to extend our lifespan while preserving health and vitality, has been a fascination throughout human history. In the quest for longevity, medical science has made significant strides, unveiling the roles of cellular processes, senescent cells, mitochondrial function, and telomere health in the aging process. Alongside theseRead
Longevity Medicine 101: Part 2
Key Longevity Nutrients In the relentless pursuit of longevity, scientific exploration has uncovered the potential of natural compounds to impact cellular health and extend lifespan. Among these compounds, pterostilbene stands out for its remarkable effects on longevity through the induction of autophagy—an essential cellular maintenance process. Autophagy orchestrates the recyclingRead
Harnessing Key Nutrients and Topical Marvels for Radiant Aging Inside and Out
In the realm of healthy aging, a realm where time and science converge, lies a treasure trove of potent key nutrients and topical wonders that can transform the way we approach the aging process. Here we’ll explore the therapeutic properties of L-Baiba, ac-11 cat’s claw, 2-HOBA, bergamot, and spermidine –Read