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Enzyme PKM2 promotes Th17 Cell Differentiation and Autoimmune Inflammation
An enzyme associated with energy production in cells also participates in the differentiation of immune cells involved in exacerbated autoimmune inflammation. The discovery could lead …
Common Kitchen Ingredient, Baking Soda, Reduces Autoimmune Response in Humans
Is it crazy to think that something as simple as a daily dose of baking soda could significantly lower the damage caused by inflammation and …
Clues Connect Estrogen and Autoimmune Disease
There is a phenomenon that scientists have yet to solve, regardless of whether a woman lives in the United States, where medical care is relatively good, or third world nations, where medical care is often scarce: women are less likely to die from infectious diseases than men. The lower death rate has been attributed to a beneficial, yet unexplained effect estrogen has on the immune system. Females of child-bearing age are more resistant to infectious disease and have an increased risk of systemic lupus erythematosus (SLE). This study hypothesized that estrogen-induced gene expression could establish an immunoactivated state which would render enhanced defense against infection, but may be deleterious in autoimmune development.By Nicholas A. Young, Lai-Chu Wu, et al, Estrogen modulation of endosome-associated toll-like receptor 8: An IFNα-independent mechanism of sex-bias in systemic lupus erythematosus. Clinical Immunology, March 2014
Integrative Solutions for Thyroid Autoimmune Disease
Autoimmune diseases are a group of disorders in which the immune system dysfunctions and attacks host tissues. Although the pathogenesis of autoimmune thyroid disease has not been elucidated, there are several factors that have been associated with the disorder. Factors include genetic predisposition, nutrient deficiencies, use of certain medications affecting thyroid function, and environmental factors including exposure to radiation, heavy metals, and chemical contaminants. Thyroid disorders are often treated with drug therapy, which often have serious side effects and do not necessarily treat the underlying condition leading to the thyroid dysfunction. In recent years there has been increased interest in herbs and supplements as individuals take more interest in their health and well being…
The Vagus Nerve: New Understandings, Emerging Research and Implications for Overall Wellness.
In recent years, the vagus nerve has become a topic of great interest, especially as it relates to stress, anxiety, depression, mood and sleep. Social …
Heart Failure or Therapy Failure? Toxins Cause Cardiomyopathy
Because cardiomyopathy presenting as clinical heart failure is a condition typically involving multiple factors, there is no single clinical protocol that can be considered the optimal treatment plan.
Phase IIb RCT-EPA Trial: Unveiling the Potential of MAG-EPA in Prostate Cancer Management
A Grim Reality: The Prostate Cancer Burden Prostate cancer remains a critical public health issue, affecting the lives of men across the globe. In the …
Beyond the Kidney Stone: Are Oxalates Affecting Your Patients?
Are you missing the possibility of oxalates contributing to your patient’s fatigue, inflammation, pain, or chronic infections? In the absence of kidney stones, dietary oxalate …
The Toxic Nutrient Triad A little: good. Just a little more: bad
Most clinicians are familiar with the concept that when a little is good, more is often better, but a lot is still reliably toxic. This results in the mindset of there being little chance of doing harm with supplementing a “little,” especially when the supplements involved are well-known and relatively popular supplements, widely regarded as being beneficial without question.
Genetics, Genomics and Personalized Medicine: using recent advances in genetic testing to personalize treatment protocols.
Of the many advances in modern medicine, few are as exciting and promising as those in the field of genetics and genomics. Emerging technology and …
