Among PD patients, those with SIBO and/or H. pylori had more unpredictable motor fluctuations. SIBO treatment resulted in significantly improved motor fluctuations without interfering with levodopa efficacy. Since PD is a progressive disease, optimizing gut health will need to be ongoing.
Every so often, a scientific article hits the press, causing patients to question their supplement regimens. A new publication has raised questions about glucosamine, a popular supplement used for arthritis and joint health, and its possible link to Alzheimer’s disease (AD).
Melatonin is widely known for regulating the sleep–wake cycle, but its clinical potential extends far beyond circadian support. Synthesized primarily by the pineal gland, and to a lesser extent in peripheral tissues, melatonin functions as a potent antioxidant, an anti-inflammatory and immunomodulatory agent, a neuroprotective molecule, and an adjunctive anticancer therapy.
Modified Citrus Pectin Blocks Gal-3 to Protect Against Post-Stroke Brain Injury A growing body of data points to microglial neuroinflammation as a contributing factor in ischemic stroke injury — driven by high levels of galectin-3 (Gal-3), a master proinflammatory alarmin protein. Research shows that Gal-3 promotes unregulated microglial activation andRead
Curcumin and the Blood Brain Barrier: Neuroprotective effect of turmeric extract in combination with its essential oil and enhanced brain bioavailability in an animal model. Banji D, Banji OJ, Srinivas K. BioMed Res Int. 2021; (January): 1-12 PURPOSE: The study evaluated the neuroprotective effect and pharmacokinetic profile of turmeric extractRead
There’s no doubt that we need to drastically improve our health. The fact that 60 percent of Americans are taking some kind of prescription drug should set off alarms in everyone. Synthetic medicines typically create more problems than they claim to solve. They are “one track” solutions to problems thatRead
In this video, Josh Helman, MD discusses the pathogenic mechanisms of the pro-inflammatory immune protein galectin-3 and its role in neurodegenerative diseases, biofilm formation, autoimmunity and other critical conditions. An expert in the fast-growing field of galectin-3 research, Dr. Helman shares key research findings, as well as clinical pearls onRead
Cognitive impairment and the development of Alzheimer’s disease are recognized risk factors in type 2 diabetes mellitus. Research continues to link metabolic dysregulation and specifically, insulin resistance, with Alzheimer’s disease and other forms of cognitive loss. Galectin-3 Fuels Diabetes and Cognitive Decline Emerging research into the beta-galactoside binding protein Galectin-3 (Gal-3) offersRead
Over the last decade or so, research interest in the pro-inflammatory and pro-fibrotic immune protein galectin-3 (Gal-3) has skyrocketed. Today, thousands of published scientific papers—including longitudinal cohort studies—point to the driving role of galectin-3 in the pathogenesis of our most serious degenerative conditions, from chronic kidney disease and acute kidneyRead
Our podcast, featuring Karta Purkh (“KP”) Singh Khalsa, AD, a Dietitian-Nutritionist and Ayurveda expert, international lecturer and author of 31 books on natural healing topics, is a must-listen for anyone interested in a natural approach to neurology. Khalsa will share easy-to-apply clinical approaches that empower patients and professionals and toRead
