Chris D. Meletis, N.D. 
Why do some patients experience recurring immune challenges as the seasons change? One possible piece of the puzzle involves the relationship between endocannabinoid signaling, adrenal stress, and immune regulation.
Summer is a window to rebuild physiological reserves—this clinician-focused piece explains how CBD and beta‑caryophyllene support endocannabinoid tone and stress resilience.
Summer patients face a perfect storm of UV exposure, intense exercise, insect bites, and heat‑driven oxidative stress. This clinical review explains how the endocannabinoid system orchestrates inflammatory resolution and how CBD and beta‑caryophyllene—working through FAAH, TRPV1, and CB2—can support skin health, sports recovery, and acute inflammatory reactions in integrative practice.
For thousands of years, cannabis has been used by people suffering from pain, including joint-related disorders.1 Today, joint pain is the largest medical reason for requesting use of the drug.1 In comparison, it is only relatively recently that researchers have started to investigate cannabidiol (CBD), a non-psychoactive component of cannabis, forRead
look for a nutrient‑dense multivitamin-phytonutrient formula designed to support antioxidant defense, cellular energy production, cardiometabolic health, and visual-cognitive function across the lifespan. A multi with the combination of vitamins, minerals, and phytonutrients makes it ideal for anyone who is not eating the recommended amounts of fruits and vegetables.
Inflammaging is a form of chronic low-grade inflammation associated with aging and increased risk of multiple chronic diseases. This article reviews key drivers of inflammaging and clinical strategies—including lifestyle interventions and targeted nutrients such as curcumin, omega-3s, cannabidiol, and beta-caryophyllene—to support a healthy inflammatory response in aging patients.
The omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have long been known to provide significant health benefits. More recently, a molecular mechanism has emerged that explains how they support a healthy inflammatory response. It’s also clear that to trigger this anti-inflammatory mechanism, a sufficient amount of bioavailableRead
Immune defense can be compared to a sport like baseball. You want to have all the bases covered with nutritional support. Combining a Multivitamin with Immune Support is the perfect double play to defend against all types of immune health challenges. This synergy between foundational micronutrients and powerful botanicals createsRead
In the course of one year, the U.S. population contracts approximately 1 billion colds.1 Influenza accounts for 20-25 million doctor visits.1 During the fall and winter, patients are at an increased risk. Going back to school can be a stressful time for many children, and the stress can lower theirRead
The endocannabinoid system (ECS) and endocannabinoid deficiency is an often neglected aspect of improving patients’ health. I liken it to adrenal fatigue and how adrenal dysfunction leads to low cortisol production and the resulting inflammation. Just as we can support the health of the adrenal glands, we can support theRead
