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New Theory on Atherosclerosis: Massively Calcified Endosome Death

Anti-Inflammatory Function of HDL Cholesterol
Larry Weisenthal, M.D., Ph.D., announced today (July 22) new unpublished findings that may lead to a better understanding on the cause of atherosclerosis. Dr. Weisenthal, a physician and researcher, says he discovered a previously unknown biological mechanism that accounts for vascular calcification, or hardening of the arteries. Dr. Weisenthal has

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Integrating Diet and Physical Activity in Type-2 Diabetes Therapy to Reduce Inflammation

inflammation
As studies show, inflammation plays a major role in diabetes-associated cardiovascular disease (CVD). Yet, many clinics are reluctant to integrate diet and physical activity interventions into healthcare settings and reduce markers of inflammation and risk of CVD in patients with type 2 diabetes (T2D). This study examined the systemic markers

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Dark Chocolate Improves Walking in Patients With Peripheral Artery Disease

This interventional study measured the acute effect of dark chocolate on walking distance autonomy (WDA), artery dilatation and NOX2‐mediated oxidative stress in a population affected by moderate‐severe. Previous studies with antioxidant infusion provided evidence that oxidative stress is implicated in impairing WDA, while its inhibition was associated with maximal walking distance (MWD) improvement. In PAD patients dark but not milk chocolate acutely improved walking autonomy with a mechanism possibly related to an oxidative stress‐mediated mechanism involving NOX2 regulation.

Compelling Research on Vitamin D Supplementation for Blood Pressure Reduction

New genetic research provides compelling evidence that low levels of vitamin D have a causal role in the development of high blood pressure (hypertension). The findings, published in The Lancet Diabetes & Endocrinology (June 26, 2014), suggest that vitamin D supplementation could be effective in combating some cases of hypertension. “In view of the costs and side effects associated with antihypertensive drugs, the potential to prevent or reduce blood pressure and therefore the risk of hypertension with vitamin D is very attractive”, said study leader Professor Elina Hyppönen from the University of South Australia.

Drop Diastolic & Systolic Blood Pressure with Yoga

Drop Diastolic and Systolic Blood Pressure with Yoga

Lifestyle modification is a cornerstone of hypertension (HPT) treatment, yet most recommendations currently focus on diet and exercise and do not consider stress reduction strategies. Yoga is a spiritual path that may reduce blood pressure (BP) through reducing stress, increasing parasympathetic activation, and altering baroreceptor sensitivity; however, despite reviews on yoga and cardiovascular disease, diabetes, metabolic syndrome, and anxiety that suggest yoga may reduce BP, no comprehensive review has yet focused on yoga and HPT. By Anupama Tyagi, MA, PhD(c) and Marc Cohen MBBS(Hons), PhD, BMedSc(Hons), FAMAC, FICAE, published Alternative Therapies in Health Medicine, Vol. 20, No. 10.

Apathy Aside, Six Factors to Reducing Global Health Risks

The biggest threat to global health and wellness can be narrowed down to six, preventable non-communicable diseases: respiratory illness from tobacco use, harmful alcohol use, salt intake, high blood pressure and blood sugar, and obesity. According to a May 2014 Lancet study, if nations could reduce target levels for these lifestyle related diseases in the next 25 years, 37 million early deaths would be prevented. But by not reaching these targets, an additional 10.5 million deaths would occur as compared to the 28.3 million who died in 2010. And while experts say this could be possible, critics say apathy from leadership is the biggest obstacle to achieving the desired target.

Molecular Secrets Discovered for Resveratrol’s Health Benefits

Resveratrol has been much in the news as the component of grapes and red wine associated with reducing “bad cholesterol,” heart disease and some types of cancer. Also found in blueberries, cranberries, mulberries, peanuts and pistachios, resveratrol is associated with beneficial health effects in aging, inflammation and metabolism. Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now identified one of the molecular pathways that resveratrol uses to achieve its beneficial action.

Palmitoleic Acid Research Review

Anti-Inflammatory Function of HDL Cholesterol

Within the world of essential fatty acids, a significant amount of interest is reserved for omega 3s and specifically for eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Another omega is gaining prominence called omega-7 (n-7), a palmitoleic acid also known for supporting cardiovascular health. When researchers look at the cardio-value of the Mediterranean diet, they see a complex interaction between multiple fatty acids, including omega-3s, omega-6s, omega-9s and omega-7s. The balance of these fats is crucial for overall wellness and longevity. The focus for this slideshow is palmitoleic, a lesser known but the fifth most commonly abundant fatty acid in the body. This is a review of the most recent research on Omega-7s.

A Case for Ending Calcium Supplements

Should physicians stop prescribing calcium supplements for bone loss? Ian Reid makes a case for ending the practice. Calcium supplements may have little role to play in the modern therapeutics of osteoporosis. Therapy today should be based around prescribing safe and effective anti-resorptive drugs to individuals demonstrated to be at increased risk of future fractures.

Chronic Inflammation and the Western Diet

Chronic inflammation is the 21st century’s leading health epidemic. It is the single common factor that contributes to the development and progression of chronic illnesses, many of which can be caused and modified by diet. As seen in this commentary by John Neustadt, ND, pathologies once viewed as unrelated are now grouped into the category of “inflammatory disease” including: atherosclerosis, dementia, arthritis, vasculitis, diabetes, and autoimmune diseases. In this report, Neustadt reviews the anti-inflammatory benefits of a “prudent diet,” including the Paleolithic diet and the Mediterranean diet. Though the Paleo diet is more restrictive in grain, legumes, dairy and potato consumption than the Med diet, both have significant overlap in macro and micro-nutrients.

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