Glutathione: Physiological and Clinical Relevance

As the risk of exposure to persistent organic pollutants (POPs) grows, research is looking at the role of glutathione and modulating disease risk. Joe Pizzorno ND and Joseph Katizinger ND review glutathione (GSH) and how altered GSH status has been implicated in a number of chronic, acute, and age-related diseases, as well as the aging process itself. In this review, the authors briefly describe glutathione physiology and the clinical implications of altered GSH homeostasis, as well as research on the use of various forms of glutathione as a therapeutic strategy. By Joe Pizzorno ND and Joseph Katzinger, ND, published in J of Restorative Medicine, Vol. 1, No. 1

Apathy Aside, Six Factors to Reducing Global Health Risks

The biggest threat to global health and wellness can be narrowed down to six, preventable non-communicable diseases: respiratory illness from tobacco use, harmful alcohol use, salt intake, high blood pressure and blood sugar, and obesity. According to a May 2014 Lancet study, if nations could reduce target levels for these lifestyle related diseases in the next 25 years, 37 million early deaths would be prevented. But by not reaching these targets, an additional 10.5 million deaths would occur as compared to the 28.3 million who died in 2010. And while experts say this could be possible, critics say apathy from leadership is the biggest obstacle to achieving the desired target.

Molecular Secrets Discovered for Resveratrol’s Health Benefits

Resveratrol has been much in the news as the component of grapes and red wine associated with reducing “bad cholesterol,” heart disease and some types of cancer. Also found in blueberries, cranberries, mulberries, peanuts and pistachios, resveratrol is associated with beneficial health effects in aging, inflammation and metabolism. Scientists from the Florida campus of The Scripps Research Institute (TSRI) have now identified one of the molecular pathways that resveratrol uses to achieve its beneficial action.

Palmitoleic Acid Research Review

Anti-Inflammatory Function of HDL Cholesterol

Within the world of essential fatty acids, a significant amount of interest is reserved for omega 3s and specifically for eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Another omega is gaining prominence called omega-7 (n-7), a palmitoleic acid also known for supporting cardiovascular health. When researchers look at the cardio-value of the Mediterranean diet, they see a complex interaction between multiple fatty acids, including omega-3s, omega-6s, omega-9s and omega-7s. The balance of these fats is crucial for overall wellness and longevity. The focus for this slideshow is palmitoleic, a lesser known but the fifth most commonly abundant fatty acid in the body. This is a review of the most recent research on Omega-7s.