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For the Assessment of Intestinal Permeability, Size Matters

Inflammasomes and colon cancer

The purpose of this review is to demonstrate that an intestine leaky to small molecules can be impermeable to large antigenic molecules. The author proposes that the permeability of the epithelium to very small sugar molecules such as lactulose/mannitol—used for the past 50 years to gauge intestinal permeability…

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