Large observational cohorts, Mendelian-randomization genetics, and post-hoc analyses of phase‑3 trials link low 25(OH)D to higher MS risk and MRI activity. This practical, nontechnical summary for naturopathic and holistic clinicians reviews evidence, sensible target ranges, safe dosing approaches, monitoring, and how to integrate vitamin D into prevention and supportive care.
This clinical briefing connects recent mechanistic findings on EBV reprogramming of autoreactive B cells to HPA axis–mediated failure of cytotoxic surveillance and enteric immune dysfunction. It outlines measurable upstream markers — diurnal cortisol/DHEA profiles (Fluids-IQ SHP), circadian inversion patterns, and midday enteric melatonin — that can identify patients at elevated risk for EBV-driven autoimmunity and inform earlier, mechanism-targeted interventions.
A paper published recently in BMJ Nutrition, Prevention & Health documents remission of type 2 diabetes among patients following a low-carb diet as well as significant improvements in metabolic health among patients with decreases in HbA1c who didn’t achieve remission. A small practice in the UK has been using low-carbohydrate diets forRead
Clear, systems-based explanation of why cannabis dependence persists after quitting and what staged recovery strategies target the underlying biology.
Findings from a new study on vitamin D and autism shed light on the possible beneficial effects of vitamin D in regulating pro-inflammatory and anti-inflammatory markers, including TNF-α, and IL-37, respectively, as well as alleviating the behavioral symptoms of children with ASD.
This review gives practitioners a practical roadmap to recognize B‑vitamin insufficiency, interpret labs, and choose evidence‑based repletion regimens.
Research published in Progress in Lipid Research clarifies how PS and DHA team up to enhance survival pathways in the brain, shape the brain’s synaptic release, and even influence memory. The study also highlights how diet, alcohol, and targeted supplements are involved and impact brain signaling.
A quick dive into PubMed yields numerous human studies on resveratrol in the past year alone. These recent studies show benefits for patients with osteoarthritis, cardiometabolic disease, Alzheimer’s disease, COVID-19, polycystic ovarian syndrome (PCOS), and periodontal disease. Its antioxidant and anti-inflammatory actions make resveratrol a good consideration for patients’ baseline health regimens.
Arguably, the most prominent ‘sleeper’ disease that contributes to 1 in every 2 to 3 hospital deaths is sepsis.1 Fueled by lipopolysaccharide (LPS)2— referred to clinically as endotoxin when it activates an immune response3— LPS was primarily viewed as an acute trigger of sepsis and systemic inflammatory response syndrome. Today,Read
Navigating toxin-related illnesses, particularly those involving mold exposure and mycotoxins, can feel overwhelming. However, the availability of evidence-based testing methods provides a clearer path forward. By understanding the range of laboratory assessments, clinicians can make more informed clinical decisions, differentiate between exposure and illness, and develop targeted treatment plans.
