Many sinusitis patients don’t have a lingering infection—they have a chronic inflammatory reaction to fungi. This post reviews a key paper on chronic rhinosinusitis, explains the fungal–eosinophilic model, and explores how intranasal Amphotericin B can help reduce inflammation, improve symptoms, and potentially delay or avoid surgery.
Join functional medicine pioneer Dr. Tom O’Bryan, DC, CCN, DACBN, CIFM, as he shares breakthrough research, clinical strategies, and functional medicine frameworks to understand, diagnose, and effectively address the complex pathology of endotoxin exposure and its impacts on health span, longevity, and clinical outcomes. In today’s age, patients are presentingRead
This episode, Chris Meletis, ND equips clinicians with a practical, layered approach to identifying, modulating, and resolving inflammation—across acute flare-ups, chronic systemic inflammation and disease-specific contexts—using nutrition, lifestyle, and targeted supplementation.Inflammation is not the enemy—but dysregulated, unresolved inflammation is the root of most chronic disease. Join Chris and Rob asRead
Arguably, the most prominent ‘sleeper’ disease that contributes to 1 in every 2 to 3 hospital deaths is sepsis.1 Fueled by lipopolysaccharide (LPS)2— referred to clinically as endotoxin when it activates an immune response3— LPS was primarily viewed as an acute trigger of sepsis and systemic inflammatory response syndrome. Today,Read
