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A Rationale for an Approach to Preventing and Treating Bisphosphonate-related Osteonecrosis of the Jaw With Vitamin K2 Menaquinone-4

In this article, the authors describe the Neustadt-Pieczenik Collagen Damage and Restoration Hypothesis, which proposes that medical professionals may prevent and treat osteoporosis and bisphosphonate-related osteonecrosis of the jaw successfully by protecting bone collagen from damage and by stimulating production of new bone collagen. They posit that collagen…

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