Christine Krall, ND 
Weight management extends beyond counting calories, as we know that hormones, inflammation, digestive capacity, body composition, and even our gut microbiome can influence metabolism. The gut microbiome may influence how the body digests food, absorbs nutrients, and metabolizes macronutrients.
While long-COVID has been associated with multiple symptoms across multiple organ systems, this article will mainly focus on the POTS (Postural Orthostatic Tachycardia Syndrome) phenotype, its association with MCAS (Mast Cell Activation Syndrome), and treatment approaches. The proposed treatment approaches may also help other long-COVID symptoms.
Every cell needs energy to function. Learn how mitochondria help make ATP, why they’re abundant in high-demand tissues, and what else these organelles do.
Its proposed role in enhancing cellular DNA repair and supporting the skin’s response to ultraviolet-induced damage has prompted investigation into whether supplementation may reduce skin cancer incidence in individuals at elevated risk. Current evidence suggests that nicotinamide may represent a safe, accessible, and relatively inexpensive strategy for skin cancer prevention in predisposed populations.
Today’s cardiometabolic care is moving beyond a singular focus on LDL cholesterol toward a more comprehensive therapeutic strategy. Properly formulated and prescribed, niacin merits renewed consideration as an evidence-based nutritional intervention that favorably impacts multiple lipid parameters associated with atherosclerotic CVD.
Daylight and artificial light at night suppress melatonin secretion, which is why we tell our patients to turn off devices before bedtime. Even household lighting at night can contribute to this effect, and it’s important to choose lighting that’s better aligned with natural circadian rhythms. Some studies have shown that typical home lighting induces significant melatonin suppression, up to 50%.
Among PD patients, those with SIBO and/or H. pylori had more unpredictable motor fluctuations. SIBO treatment resulted in significantly improved motor fluctuations without interfering with levodopa efficacy. Since PD is a progressive disease, optimizing gut health will need to be ongoing.
Every so often, a scientific article hits the press, causing patients to question their supplement regimens. A new publication has raised questions about glucosamine, a popular supplement used for arthritis and joint health, and its possible link to Alzheimer’s disease (AD).
Even acknowledging the potential benefits of carnivore and keto diets for some conditions, it’s hard to ignore the extensive meta-analytic evidence linking higher fiber intake with better health outcomes. For most people, increasing fiber intake is a low-risk change with considerable potential upside.
While lifestyle changes are important, compliance can be challenging, and other strategies like targeted supplements can help manage oxidative stress, inflammation, and insulin resistance. Notably, this article includes several meta-analyses of randomized controlled trials (RCTs) examining the effects of various nutrients on MASLD, providing a robust synthesis of the available evidence. Enhanced efficacy is seen when these therapies are paired with a Mediterranean diet and other healthy lifestyle changes.
